"I" is for the Indian Affairs Commission. The first Indian Affairs Commission was established by the Lords Proprietors in the 1680s, but did not succeed in arbitrating disputes between Indians and European settlers. A later commission, created in 1710 by the Commons House of Assembly was intended primarily to regulate the Indian deerskin trade. Its most noted commissioner was Thomas Nairne.
After the French and Indian War, the British Government assumed primary responsibility for Indian relations and after the Revolutionary War, control of Indian affairs passed to the federal government. In 2000 an unofficial Indian Affairs Commission was established in South Carolina as a non-profit organization. It is made up of representatives from ten different Native American groups in the state.