The South Carolina Department of Public Health (DPH) has confirmed five additional measles cases in the Upstate, bringing the total number of illnesses in the current outbreak to 49. In all, 52 people have been infected in the state this year.
Two of the new cases are household members of known measles cases who were in quarantine. The origin of the other three has not yet been identified.
According to the SIMON statewide vaccination reporting system, there has been a 110% increase in measles-mumps-rubella (MMR) vaccinations given by providers (pediatricians, pharmacies, clinics, etc.) in Spartanburg County for October 2025 compared to October 2024. 669 doses of the MMR vaccine were administered in October 2024, and 1,405 were administered last month, an increase of 736.