Hello Gardeners, I’m Amanda McNulty with Clemson Extension and Making It Grow. Many people try to spray insecticides on the nests of eastern tent caterpillars or fall webworms. The webs, however, protect the caterpillars and usually the nests are too high to effectively reach with your sprayer. Trying to burn the nests may start a fire or badly damage the tree. One specialists says that if you can safely reach the nest, use the five-fingered, digital, integrated pest management approach.